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br Materials and methods br Results br Discussion D abbrevia
2022-02-21

Materials and methods Results Discussion D. abbreviatus larvae are voracious feeders, and the nutrients consumed as part of their diet are broken by gut proteases and utilized for growth and development. Since proteases play an important role in larval and adult food digestion, it is import
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Renal disease is characterized by aberrant fibrotic remodeli
2022-02-21

Renal disease is characterized by aberrant fibrotic remodeling of renal tissue, elevated apoptosis in kidney tissue, and eventual organ failure. In addition, patients with renal disease are more likely to suffer from systemic hypertension due to oxidative damage (reviewed in Ref. [18]). Treatment of
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Pasireotide Glycogen synthase kinase GSK is an evolutionaril
2022-02-21

Glycogen synthase kinase-3β (GSK-3β) is an evolutionarily conserved serine/threonine kinase that plays multifaceted role in diverse cellular and neurophysiological processes [8]. GSK-3β is regulated by inhibitory serine and stimulatory tyrosine phosphorylation on Ser9 and Tyr216 respectively [9]. Dy
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br GPR GPR has been described as
2022-02-21

GPR55 GPR55 has been described as a type 3 cannabinoid receptor due to its ability to detect endocannabinoids and may play a role in the endocannabinoid lipid sensing system [28]. GPR55 is activated by both cannabinoid endogenous agoinsts (endocannabinoids) and non-cannabinoids fatty acids namely
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Several studies have sought a cross relationship between
2022-02-21

Several studies have sought a cross-relationship between commensal bacteria-derived metabolites and the Gprs (Blad et al., 2012). Gpr81 is expressed primarily in adipocytes, and hence, lactate-Gpr81 interaction inhibits lipolysis (Cai et al., 2008, Liu et al., 2009). Lactate reduced inflammation by
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GnRH ant have been designed to obtain
2022-02-21

GnRH-ant have been designed to obtain pharmacological compounds to block the pituitary–gonadal axis without the undesirable flare effect exerted by GnRH itself or by the GnRH-a (see Section 2.2). GnRH-ant competitively block the binding of GnRH to GnRHRs (Schally, 1999; Tan & Bukulmez, 2011); they p
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Cichlasoma dimerus as most teleost
2022-02-21

Cichlasoma dimerus, as most teleost fish species, present neurons expressing GnRH3 (Pandolfi et al., 2005). As in most CID 755673 mg species, the neurons expressing GnRH3 are mainly located in the NOR, although few neurons were detected in the olfactory bulb, ventral telencephalon and the POA (Gonzá
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Our experimental results demonstrated http www apexbt com
2022-02-18

Our experimental results demonstrated marked variability in antioxidant defenses and oxidative damage in Crassostrea gigas between the visceral mass and the gill after the treatments by rifampicin and verapamil through determining the changes of the activity of SOD and POD and MT content. It has bee
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It is known that hypercapnia
2022-02-18

It is known that hypercapnia, as well as hypoxia, can result in a decrease in body temperature, but the mechanisms involved are not very well known (Barros and Branco, 1998; Saiki and Mortola, 1996). One Nile Red is that when there is an acute hypercapnic exposure, acidosis plays an inhibitory role
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It is well known that GPCR
2022-02-18

It is well known that GPCR responsiveness desensitizes after prolonged exposure to agonists through several mechanisms such as receptor phosphorylation, arrestin binding and internalization (Dhami and Ferguson, 2006). Therefore, in the present work we decided to study whether group I-mGluR signaling
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Transmembrane AMPA receptor regulatory proteins
2022-02-18

Transmembrane AMPA receptor regulatory proteins (TARPs) are a relatively newly discovered protein family. Prototypic TARP, stargazin, was found by a spontaneous mutation in ataxic stargazer mouse line as a homologous protein to γ1 calcium channel subunit (Letts et al., 1998). The role of stargazin i
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Acknowledgments br Introduction The gut derived
2022-02-18

Acknowledgments Introduction The gut-derived hormone oxyntomodulin (OXM) is a naturally occurring dual agonist of both the glucagon receptor (GCGr) and glucagons-like peptide 1 receptor (GLP-1r). Structurally OXM is the 29 (S)-Methylisothiourea sulfate of glucagon with a C-terminal octapeptide
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nociceptin receptor One may carefully evaluate the concept p
2022-02-18

One may carefully evaluate the concept ‘pancreas derived GLP-1′ as this may dependent on the specificity of the nociceptin receptor used in immunohistochemistry or radiommunoassays. If either a side-viewing antibody or a C-terminal wrapping antibody raised against GLP-1 is applied one may also iden
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Thus this work aims to evaluate the effect of
2022-02-18

Thus, this work aims to evaluate the effect of tannic dgat inhibitor on β-galactosidase activity, by observing the variations in the molecular interaction kinetic parameters ( and ). Besides, these data were correlated with the modifications that the tannin caused to the enzyme’s secondary structure
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br Materials and methods br Results br Discussion In the
2022-02-18

Materials and methods Results Discussion In the absence of vascularization phenomena, endothelial cells (ECs) are among the most quiescent cells of the body [27]. ECs proliferation is significant during embryogenesis, as the vasculature is being formed, while in the adult life takes place o
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